摘要
我们应用中和性McAb对陕西省1979～1988年从病人分离的70株Polio病毒进行型内抗原分析,将32株Ⅰ型病毒分为PI—2(28株)、P1—3(3株)和P1—5(1株)3个类型。27株Ⅱ型病毒分为P2—1(19株)和P2—2(8株)2个类型,11株Ⅲ型病毒分为P3—1(5株)、P3—2(3株)、P3—3(1株)和具有新抗原特征的陕P3—1(2株)4个类型。结果反映了陕西省近10年Polio病毒型内抗原特征类型的分布、变迁及其与疾病流行的关系。
This paper reports antigenic analysis of 70 st- rains of poliovirus isolated from polio cases in Shaanxi in 1979-1988 by neutralizing MCAb. 32 strains of type 1 poliovirus were classified into 3 groups-P1-2(28 strains), P1-3(3 strains) and P1 -5(1 strain). 27 strains of type 2 poliovirus were divided into 2 groups-P2-1(19 strains)and P2-2 (8 strains). 11 strains of type 3 poliovirus were classified into 4 groups. They were P3-1(5 strai- ns), P3-2(3 strains), P3-3(1 strains) and the new antigenic group Shaanxi/P3-1(2 strains). This res- ult indicated the close relationship between the distribution of antigenic groups of poliovirus in Shaanxi in the recent years and the polio epdemic.
关键词
脊髓灰质炎
病毒
抗原
McAb
Poliovirus Antigenic analysis
Monoclonal antibody
