摘要
目的通过观察干扰素不同用药途径治疗小儿疱疹性咽峡炎的临床疗效,探讨最佳用药途径。方法 240例疱疹性咽峡炎患儿随机分为治疗组A79例、治疗组B77例和对照组C84例,进行临床疗效比较。所有患儿均予对症支持治疗、抗病毒药物及预防并发症等传统疗法治疗,治疗组A在此治疗基础上给予重组人干扰素a1b雾化吸入,治疗组B在对照组用药基础上给予重组人干扰素a1b肌肉注射,观察3组患儿疗效,并将结果给予统计学处理。结果治疗组A、治疗组B在退热及疱疹消失平均天数方面均优于对照组C,治疗组A更优于治疗组B。3组比较差异有统计学意义(P<0.05)。结论重组人干扰素a1b治疗疱疹性咽峡炎在退热、口腔疱疹消退、进食方面均优于传统疗法,而且使用重组人干扰素a1b雾化吸入较肌肉注射效果更明显,3组比较差异均有统计学意义,且雾化吸入方便、无痛苦、安全性高,更值得临床推广应用。
Objective Observation of the clinical effection of interferon（IFN） in different approaches on herpangina of children,then search a better approacher to treatment herpangina of children.Methods 240 cases suffering from herpangina were randomly selected and divided into three groups to observe the effection.Results The average defervescence time and the average duration of the herpes were shorter in the treatment groups than those in control group. In the statistics,the difference significant（P〈0.05）.Coneulsion The results suggested that the interferon（IFN） is an effective and safe treatment.It is one of the most effective treatment therapy of herpangina with nebulization.
出处
《中外医疗》
2012年第4期18-19,共2页
China & Foreign Medical Treatment
关键词
干扰素
雾化
肌注
疱疹性咽峡炎
小儿
Interferon（IFN） Nebulization Intramuscular Herpangina Children
