摘要
目的为研究超急性排斥反应及对策，建立异种胰腺移植模型。方法以豚鼠和大鼠为供受者，用袖套法吻合静脉建立异种全胰十二指肠移植模型。结果共行 ４２次手术，成功 ３８例，均有内分泌功能，移植有效率为 １００％。结论本模型具有操作简单，冷缺血及腹主动脉阻断时间短，不易形成血栓及吻合口漏等优点，为一较实用的研究异种胰腺移植模型。
Objective To establish a guinea pig to rat pancreaticoduodenal xenograft model for studying hyperacute rejection. Methods Superior mesenteric vier-left renal vein cuff anastomases were resected. An end to side anastomasis was made between the graft duodenum and the host jejunum. Results Fortytwo operations were done, and 38 cases were successful, of which all grafts of the successful cases had endocrinium function. Conclusions This model can reduce the incidence of thrombosis and the duration of ischemia during operation. It is a simple and practical,
出处
《第一军医大学学报》
CSCD
2000年第1期30-31,共2页
Journal of First Military Medical University
