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多发性骨髓瘤的维持治疗 被引量:2

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摘要 随着对多发性骨髓瘤(MM)生物学特性认识的不断深入,其治疗也取得了很大的进展。新的强化治疗方案的应用、自体外周血造血干细胞移植(APBSCT)、纯化CD34+细胞移植、树突细胞及树突细胞疫苗的应用、干扰素、沙利度胺及三氧化二砷等的应用,显著提高了MM患者的生存期。然而,多数患者在经历较长时间的平台期后,最终仍会复发和产生耐药。为追求更满意的治疗效果,延长MM患者的生存时间,病情稳定后仍需给予维持巩固治疗。真正有效的维持治疗不仅要将疾病的危害最小化,还要延长无病生存期、总生存期及无进展生存期。
出处 《中国实用医刊》 2012年第5期90-92,共3页 Chinese Journal of Practical Medicine
基金 基金项目:国家自然科学基金项目(30900637 81070398),中国医师协会多发性骨髓瘤专项基金
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