摘要
目的探讨波依定治疗原发性高血压的临床效果。方法选取60例高血压患者,随机分为波依定组(治疗组)和硝苯地平组(对照组)各30例,治疗组给予波依定,对照组给予硝苯地平缓释片。结果治疗组的总有效率93.3%;对照组的总有效率86.7%,两组有效率比较差异具有统计学意义(P<0.01);治疗组不良反应率20%,对照组不良反应率36.7%,两组之间差异具有统计学意义(P<0.05)。结论波依定是一种长效钙离子拮抗剂,是治疗高血压较理想的长效降压药物;波依定的作用持久而缓和,安全有效,可明显地降低高血压病患者的收缩压和舒张压,且不改变患者的心率和心律,对肝、肾、血脂、血糖无影响,并能有效地维持24h的降压作用,尤适应于老年人收缩期高血压。
Objective To investigate the clinical effect of Plendil in treatment of essential hypertension.Methods Sixty patients with hypertension were randomly divided into Plendil group（treatment group） and nifedipine（control group） 30 patients in each treatment group were given Plendil,the control group received nifedipine.Results The total effective rate was 93.3%;Control group,86.7% of the total efficiency,the efficiency difference between the two groups was significant（P0.01）;treatment group adverse reaction rate of 20% in the control group 36.7% rate of adverse reactions,the difference between the two groups was significant（P0.05）.Conclusions Plendil is a long-acting calcium antagonist,is an ideal long-term treatment of hypertension,antihypertensive agents;role Plendil lasting ease,safe and effective,can significantly reduce the contraction of hypertensive patients pressure and diastolic blood pressure,and does not change the patient＇s heart rate and rhythm,liver,kidney,blood lipids,blood glucose had no effect,and can effectively maintain the antihypertensive effect of 24h,especially systolic hypertension in the elderly to adapt.
出处
《医药论坛杂志》
2011年第24期70-71,共2页
Journal of Medical Forum
关键词
波依定
高血压
治疗
Plendil
Hypertension
Treatment
