摘要
目的 IBL 样 T淋巴瘤属高度恶性肿瘤 ,由于其细胞成份的多样性 ,病理组织学上很易误诊为良性病变。现将 9例报告如下。方法 全部病例做病理组织学及免疫组化(ABC法 )检测。结果 组织学上最显著的特征是血管旁胞浆淡染透明的透明细胞显著增生 ,2例呈现弥漫增生 ,7例呈现小灶状增生。小至中等大的异型核细胞散在于小灶状增生的透明细胞周围。免疫组化染色显示透明细胞及异型核的小、中型细胞均为 T细胞来源 ,其中 CD45 RO阳性例 10 0% ,CD43阳性例 77.8% ,CD3阳性例 6 6 .7%。结论 IBL样 T淋巴瘤的诊断最重要的组织学特征是在 AIL D背景上出现透明细胞的片状或小灶状增生。
Objective IBL like T cell lymphoma is highly malignant. but may easily misdiagnose as benign lesion because of the multiplicity of cellular composition.Methods A pathologic analysis of 9 cases was studied by pathological and immunohistochemical (ABC) methods.Results The characteristic histologic finding was the proliferation of lymphoid cells with pale cytoplasm nearby the blood vessels. Sheet like proliferation of pale cell forming compartments was recognized in two cases, in other 7 cases, pale cells made irregular shaped clusters or diffuse small nests, which were rounding by medial and smaller cells with atypical nucleus and revealed 100 % CD45 +, 77 8 % CD43 + and 66 7 % CD3 +. Conclusion Focal or sheet like proliferation of pale cells in addition to the angioimmunoblastic lymphadenopathy (AILD) changes are the histologic characteristic of IBL like T cell lymphoma. Immunohistochemical staining is helpful to its diagnosis.
出处
《肿瘤》
CAS
CSCD
北大核心
2000年第2期108-110,共3页
Tumor
