摘要
目的:探讨小剂量红霉素治疗早产儿喂养不耐受的疗效和安全性。方法:将74例喂养不耐受的早产儿随机分为治疗组36例和对照组38例。对照组给予常规治疗,治疗组在常规治疗的基础上给予红霉素5 mg.kg-1.d-1静脉滴注,每天1次,治疗5～7 d。结果:治疗组的呕吐停止时间、胃潴留消失时间、腹胀消失时间、达完全胃肠道营养时间及恢复到出生体重时间,均短于对照组时间(P<0.05)。治疗组出现2例腹泻,对照组出现1例,差异无统计学意义(P>0.05)。结论:小剂量红霉素治疗早产儿喂养不耐受疗效显著,安全性好,值得推广。
Objective：To investigate the effect of low-dose of erythromycin on feeding intolerance in premature infants.Methods：Seventy-four premature infants with feeding intolerance were randomly divided into treatment group（36 cases） and control group（38 cases）.The control group received routine therapy,while the treatment group were administered intravenous injection of erythromycin 5 mg·kg-1· d-1once a day for 5-7 days in addition to the routine therapy.Results：The therapeutic effect of treatment group was superior to the control group in the extinction time of vomiting,stomach retention and abdominal distension as well as the time of nutrition getting full into the gastrointestinal tract and achieving birth weight（P0.05）.Diarrhea occurred in 2 cases in the treatment group and 1 case in the control group.There wasn′t statistical significance（P0.05）.Conclusions：The erythromycin in low-dose can improve the feeding into intolerance of premature children.It is worthly of application.
出处
《蚌埠医学院学报》
CAS
2011年第12期1339-1340,共2页
Journal of Bengbu Medical College
关键词
婴儿
早产
疾病
红霉素
喂养不耐受
infant
newborn diseases
erythromycin
feeding intolerance
