摘要
目的:探讨血清钙和C反应蛋白(CRP)对急性胰腺炎(AP)危重程度的早期预测价值。方法:检测52例轻型AP(MAP)和21例重症AP(SAP)患者发病1～4天血清钙和CRP水平,并对这2项指标预测SAP的价值进行评估。结果:入院第1天,AP患者血清CRP水平即明显增高,第2天达高峰,SAP组比MAP组增幅更为显著(P<0.01);此时CRP诊断SAP的灵敏度、特异度和ROC曲线下面积分别为87.3%、91.8%和0.924。MAP组患者血清钙无明显变化(P>0.05),而SAP组患者入院第1天血清钙水平即显著降低(P<0.01),随着时间推移,血清钙水平继续下降;血清钙诊断SAP的灵敏度、特异度和ROC曲线下面积分别为82.4%、86.1%和0.876。结论:血清钙和CRP可作为早期判断AP严重程度的可靠指标。
Objective：To study the value of serum calcium and C reaction protein（CRP） in predicting the severity of acute pancreatitis（AP）.Methods：The serum calcium and CRP were monitored on day 1,2,3 and 4 in 52 patients with mild AP（MAP） and 21 patients with severe AP（SAP）,their diagnostic value was assessed.Results：The level of serum CRP increased significantly in AP group on the the first day of admission and reached the peak on the second day,which was more obvious in SAP group than in MAP group（P0.01）.The diagnostic sensitivity of CRP was 87.3%,specificity 91.8% and AUC 0.924.No significant difference was found between the MAP group and the normal control（P0.05）,and the levels continued to desend with time goes by.Compared with the normal control group,the level of serum calcium in SAP group decreased notablely on the the first day of admission（P0.01）.The diagnostic sensitivity of serum calcium was 82.4%,specificity 86.1% and AUC 0.876.Conclusions：Serum calcium and CRP can be used as a reliable index in evaluation of the severity of acute pancreatitis.
出处
《蚌埠医学院学报》
CAS
2011年第12期1314-1316,共3页
Journal of Bengbu Medical College
关键词
胰腺炎
钙
C反应蛋白
严重度预测
pancreatitis
calcium
C reactive protein
prediction of severity
