摘要
本文通过近年来药物对肠道寡肽转运体（Human Oligopeptide Transporter1．PEPT1）功能性与活性的表达等方面的研究进展情况．旨在了解PEPT1在药物相互作用、提高药物口服生物利用度．药物靶向治疗以及个体化给药等方面的意义，为临床合理用药提高提供参考。
To understand the effects of some drugs on PEPT1 （Human Oligopeptide Transporter 1） expression and activity, and provide advices for the rational use of drug in clinic, related literatures about the regulation of PEPT1 function were Reviewed. Many drugs and hormones could affect the function of PEPT1 significantly. Studies showed that alteration in PEPT1 functioin could contribute to interactions of drugs, elevation of the drug oral bioavailability, and targeted treatment and individualized administration.
出处
《药品评价》
CAS
2011年第24期4-7,共4页
Drug Evaluation
