摘要
目的观察利多卡因、山莨菪碱联合高压氧治疗美尼尔症的疗效。方法选择2010年10月—2011年4月美尼尔症患者30例,随机分为对照组15例和治疗组15例,对照组静脉滴注10%葡萄糖注射液500mL+ATP40mg+辅酶A 100U;苯海拉明50mg口服,3次/d;盐酸氟桂利嗪胶囊(西比灵胶囊)2粒(10mg)口服。治疗组20%利多卡因20mL,盐酸山莨菪碱注射液10mg,加入10%葡萄糖注射液100mL中静脉滴注,1次/d,并应用高压氧治疗。2组均以12d为1疗程。结果 1个疗程后,对照组和治疗组总有效率分别为73.3%和93.3%,差异有统计学意义(P<0.05);治疗组对临床症状改善明显优于对照组(P<0.05)。结论利多卡因联合山莨菪碱、高压氧治疗美尼尔症疗效显著,值得临床推广。
Objective To discuss the clinical efficacy of lidocaine, anisodamine combined with hyperbaric oxygen in the treatment of Meniere＇ s disease. Methods Thirty patients were randomly divided into the treatment group and control group. 15 cases of control were given intravenous drip 10% glucose injection of 500mL ＋ ATP 40rag ＋ coenzyme A i00U ; diphenhydramine 50 mg orally, three times a day; Flunarizine hydrochloride two capsules orally, the treatment group were injected 20mL 20% lidocaine, 10 mg anisodamine and 100mL 10% glucose, once a day, on the basis of drug treatment, hyperbaric oxygen therapy was given. Results After a course of treatment,the total effective rate of the control group and treatment group were 73.3% and 93.3%, the difference was statistically significant （P 〈 0.05 ） ; the clinical symptoms of treatment group was better than control group （ P 〈 0.05 ）. Conclusion The effect of lidocaine, anisodamine combined with hyperbaric oxygen was significant in the treatment of Meniere＇ s disease. It is worthy of clinical application.
出处
《河北医科大学学报》
CAS
2011年第12期1414-1416,共3页
Journal of Hebei Medical University
关键词
高压氧
利多卡因
山莨菪碱
hyperbaric oxygenation
lidocaine
ANISODAMINE
Meniere
disease
