摘要
本文报告用杀菌试验及肥达氏反应同时检测49例确诊为伤寒病患者的血清.结果杀菌试验全部阳性,阳性率为100%;肥达氏反应36例阳性,阳性率为73.47%.两种诊断方法相比,有显著差异(P<0.005).另以非伤寒患者37例及健康人11例作对照,除1例杀菌试验阳性外,余47例均阴性.说明本试验具有特异性高,假阳性少,可早期诊断等特点.同时本试验操作简单易行,可在临床上推广应用.
Serum samples were collected from 49 confirmed cases of typhoid fever, 37 cases of non-typhoid diseases and 11 normal controls.All the above sera were tested for eliciting bactericidal antibodies to Salmonella typhi.In addition, Widal test was also performed for comparison.The results: All the 49 sera of typhoid fever cases were found to be positive by bactericidal antibody test (titre 1∶100 or above).Only 1 of the 37 non-typhoid fever cases had serum bactericidal at 1 in 100,and none of the normal controls were positive.The Widal test only detected 36 cases of the 49 cases of typhoid fever, and 5 cases of non-typhoid diseases gave false positive reactions.Thus, the bactericidal antibody test is a simple, sensitive and quite reliable test, and requires only microquantities of serum samples as compared to the test.
关键词
伤寒
杀菌试验
肥达氏反应
诊断
Bactericidal Antibody Test
Typhoid Fever
Widal Test
