摘要
目的探讨甲状腺嗜酸细胞瘤的病理特点、诊断及治疗原则。方法回顾性分析1998年1月至2008年1月收治的23例甲状腺嗜酸细胞瘤的临床资料。结果术前细针穿刺活检及术中快速病理切片确诊17例,术后石蜡病理切片确诊6例。甲状腺嗜酸细胞腺瘤21例,嗜酸细胞癌2例。行单侧甲状腺次全切除12例,单侧甲状腺腺叶切除7例,单侧甲状腺腺叶切除及峡部切除2例,甲状腺全切除术2例。切除标本中合并结节性甲状腺肿2例及甲状腺滤泡型腺瘤2例。术后均治愈,随访6个月至10年,未见复发或转移。结论结合甲状腺嗜酸细胞瘤的临床病理特点,提高术前及术中确诊率,选择适宜的手术方式和术后长期随访对甲状腺嗜酸细胞肿瘤的诊治至关重要。
Objective To investigate the clinicopathological characteristics, diagnosis and surgical treatment of thyroid Hurthle cell tumors (HCT). Methods A retrospective analysis was made on 23 patients with HCT admitted from Jan. 1998 to Jan. 2008 in our hospital. Results 17 cases were diagnosed by fine needle aspiration biopsy (FNAB) and intraoperative frozen section and 6 cases were diagnosed by postoperative pathology, The pathological report showed that 21 cases were with Hurthle cell adenomas and 2 cases with Hurthle cell carcinomas. The following surgical operations were performed, 12 cases of subtotal thyroidectomy, 7 cases of thyroid lobectomy, 2 cases of thyroid lobectomy combined with isthmusectomy, and 2 cases of total thyroidectomy. Among the 23 samples, 2 cases were complicated with nodular goiter and 2 cases with follicular thyroma. All the cases were followed up for 6 months to 10 years without recurrence or metastasis. Conclusion It is important to pay attention to clinicopathological characteristics of HCT, improve preoperative and intraoperative diagnosis accuracy, choose proper surgical procedures and have a long-time follow up for patients with thyroid HCT.
出处
《中华内分泌外科杂志》
CAS
2012年第1期32-34,共3页
Chinese Journal of Endocrine Surgery