摘要
在大鼠毁髓模型上,对由脊髓C_7～T_(10)节段发出的交感节前纤维逐节进行电刺激时,发现肺循环阻力(PVR)均有不同程度的升高,但在刺激脊髓C_7～T_4节段时PVR升高最为显著(对照值的28%),明显高于其余各节段电刺激后PVR增加的水平。刺激的脊髓节段愈高,△PVR/△SVR比值也愈大。体循环阻力(SVR)的升高则以低位脊髓节段的电刺激时更明显。提示在大鼠脊髓C_7～T_4节段存在支配肺血管运动的交感神经中枢。
This study was to localize the position of spinal center of sympathetic nerve which controls the pulmonary circulation in pithed rat model. The sympathetic preganglionic fibers arising from C7-T10 spinal segments were stimulated electrically in succession. During stimulation the pulmonary vascular rcsistance(PVR) was increased in all segments tested, most significantly in C7-T4(about 28% above control value) which was obviously higher than that of Ts-T10. In constract, the systemic vascular resistance(SVR) increased more remarkably when lower segments were stimulated. The higher the stimulated spinal segments, the larger the ratio of APVR/ASVR. The data showed that the spinal center of sympathetic nerve which regulates the vasomotion of pulmonary circulation is located in the segments C7-T4.
出处
《中国病理生理杂志》
CAS
CSCD
北大核心
1990年第2期116-118,共3页
Chinese Journal of Pathophysiology
关键词
交感神经纤维
肺循环
脊髓
Pulmonary circulation
Sympathetic fibers
Spinal cord
