摘要
目的探讨血清肌钙蛋白(IcTnI)和高敏C-反应蛋白(hs-CRP)在急性冠脉综合征(ACS)患者经皮冠状动脉介入(PCI)术后的变化及临床意义。方法采用双抗夹心ELISA法测定70例行PCI术治疗的高危ACS患者和30例经冠状动脉造影正常者血清cTnI和hs-CRP水平。结果术前ACS组血清cTnⅠ、hs-CRP水平均显著高于对照组,相比较差异有显著性(P<0.05);术后AMI组、UA组血清cTnⅠ、hs-CRP水平显著升高,与术前比较差异有显著性(P<0.05);且AMI组血清cTnⅠ、hs-CRP水平均高于UA组,相比较差异有显著性(P<0.05);血清cTnⅠ和hs-CRP水平呈显著正相关性(r=0.561,P=0.001)。结论 PCI术后血清cTnⅠ和hs-CRP水平升高。cTnⅠ和hs-CR可能会做为PCI术后冠状动脉斑块不稳定性的预测指标。
[Objective] To observe the changes and clinical significance of serum cTnⅠand hs-CRP in patients with acute coronary syndrome（ACS） after percutaneous coronary intervention（PCI）.[Methods] The serum cTnⅠand hs-CRP level of 70 cases of high-risk ACS patients and 30 cases of normal subjects by coronary angiography were measured by ELISA.[Results] Before PIC,the serum cTnⅠand hs-CRP levels of the ACS group were higher than the control group,compared the difference was significant（P 0.05）;After PCI,the serum cTnⅠand hs-CRP levels of the AMI and UA group significantly increased,compared with the level before PCI the difference was significant（P 0.05）;The serum cTnⅠand hs-CRP levels of the AMI group were higher than the UA group,compared the difference was significant（P 0.05）;The serum cTnⅠand hs-CRP levels was significantly positive correlation（r=0.561,P =0.001）.[Conclusion] The postoperative serum cTnⅠand hs-CRP levels increase,the cTnⅠand hs-CRP may be used as an indicator forecasting of coronary plaque instability in patients with ACS after PCI.
出处
《中国内镜杂志》
CSCD
北大核心
2012年第1期38-40,共3页
China Journal of Endoscopy
