摘要
目的观察早期尿激酶静脉溶栓治疗急性心肌梗塞（ＡＭＩ）的疗效及冠状动脉（冠脉）再通与早期Ｔ波倒置的相关性。方法回顾分析３４例ＡＭＩ患者采用早期尿激酶溶栓治疗与５７例ＡＭＩ患者的常规治疗作对照，观察溶栓治疗患者的再通情况及其溶栓后 ２４ ｈ内 Ｔ波倒置对判定冠脉再通的意义。结果尿激酶治疗组和对照组的冠脉再通率分别为６４．７１％和１５．７９％（Ｐ＜０．０５），发病至开始溶栓时间越短，再通率越高。早期溶栓后 ２４ ｈ内 Ｔ波倒置显示冠脉再通的敏感性和特异性分别为９０．４８％和７６．９２％。结论早期尿激酶静脉溶栓治疗可提高急性心肌梗塞疗效，降低病死率。Ｔ波倒置具有判断闭塞冠脉再通的临床价值。
Objective To study the clinical effect of early intravenous thrombolysis for putients with acute myocadial infartion (AMI) by urokinase (UK). Methods 34 cases of AMI were treated by UK and compared with 57 cases of AMI using routine treatment. The reperfusion was judged upon T wave inversion in 24 hours after thrombolysis Results The reperfusion rate of coronal artery in UK group and control group was 64. 71 % and 15. 79% , respectively. The sensitivity of reperfusion and specificity were 90. 48% and 76. 92%, respectively. Conclusion Early intravenous thrombolysis by UK can improve therapeatical efficacy and reduce mortality of AMI. T wave inversion has clinically predictive value for of reperfusion.
出处
《临床内科杂志》
CAS
2000年第2期90-92,共3页
Journal of Clinical Internal Medicine
关键词
急性
心肌梗塞
尿激酶
静脉溶栓疗法
Urokinase
Thrombolysis therapy
Myocardial Infarction/therapy
