摘要
目的观察持续气道正压通气(continuous positive airway pressure,CPAP)对2型糖尿病合并阻塞性睡眠呼吸暂停综合征患者的治疗过程中的血糖变化.方法将40例2型糖尿病合并阻塞性睡眠呼吸暂停综合征患者随机分为治疗组(25例)及对照组(15例),两组均使用胰岛素强化治疗控制血糖,配合饮食控制及运动.治疗组在降糖基础上联合应用CPAP治疗.治疗3月后观察治疗组及对照组患者血糖变化.结果经过3个月的治疗,治疗组患者空腹血糖、餐后血糖、糖化血红蛋白(HbA1c)及呼吸紊乱指数(AH)I较治疗前下降(P<0.05),对照组空腹血糖、餐后血糖、糖化血红蛋白(HbA1c)及呼吸紊乱指数较治疗前下降(P<0.05),组间比较治疗组较对照组血糖、呼吸紊乱指数下降更显著(P<0.01).结论 CPAP治疗对2型糖尿病合并阻塞性睡眠呼吸暂停综合征患者有利于改善其高血糖状态.
Objective To investigate the blood sugar content changes of patients with Type2 diabetes and Obstructive Sleep Apnea Hypopnea Syndrome （OSAHS） treated by continuous positive airway pressure （CPAP）. Method 40 patients with Type2 diabetes and OSAHS were randomly divided into two groups. The control group, which included 25 patients, and the treatment group, which included 15 patients, were treated by intensive insulin therapy to control blood sugar content, combined with diet exercise control, while treatment group received CPAP treatment at the same time. The experiments lasted for three months and blood sugar content was monitored throughout the whole period. Results After three months treatment, both groups showed decreasing in blood sugar contents in terms of fasting blood sugar and 2 hours postprandial blood sugar. The treatment group （P 〈 0.01） had more significant decrease in blood sugar content than the control group （P 〈 0.05 ）. Conclusion CPAP has positive effect in treating patients with Type 2 diabetes and OSAHS.
出处
《昆明医学院学报》
2012年第1期74-77,共4页
Journal of Kunming Medical College
基金
云南省教育厅科学研究基金资助项目(2010C112)
