摘要
鲍曼不动杆菌已成为医院感染的重要病原菌。随着广谱抗生素的广泛应用,鲍曼不动杆菌的耐药率逐渐增高。临床上已出现了泛耐药菌株,而且其分离率也逐年上升,已成为临床抗感染治疗的难题。此文对近年来国内外泛耐药鲍曼不动杆菌的耐药机制、分型方法、临床治疗策略及最新研究等方面作一综述。
Acinetobacter baumannii has become an important pathogen of nosocomial infection. With the extensive application of broad-spectrum antibiotics, the resistance rate of Acinetobacter baumannii is increasing gradually. It has been a clinical pan-resistant strains, and the separation rate increased year by year, which has become a clinical problem of anti-infective therapy. The resistance mechanisms of pan-resistant Acinetobacter baumannii, typing methods, clinical treatment strategies and the latest research in domestic and foreign in recent years are reviewed in this paper.
出处
《国际流行病学传染病学杂志》
CAS
2012年第1期56-59,共4页
International Journal of Epidemiology and Infectious Disease
关键词
鲍氏不动杆菌
泛耐药
耐药机制
基因分型
Acinetobacter baumarmii
Pan drug resistant
Resistance mechanisms
Genotyping