摘要
目的:研究藏产鳞腺杜鹃地上部分的化学成分。方法:利用多种色谱方法对其成分进行分离纯化,通过理化性质及NMR、MS波谱数据解析鉴定化合物的结构。结果:从中分离得到18个化合物,分别鉴定为:何帕醇-B(1),羽扇豆醇(2),熊果酸(3),扁蓄苷(4),槲皮素(5),杨梅素(6),金丝桃苷(7),杨梅素-3'-O-β-D-吡喃木糖苷(8),(+)-花旗松素-3-O-α-L-吡喃阿拉伯糖苷(9),(+)-花旗松素-3-O-β-D-吡喃葡萄糖苷(10),lyoniside(11),confluentin(12),2-(4-hydroxyphe-nyl)-ethyl triacontanoate(13),2,6-二甲氧基-4-羟基苯酚-1-O-β-D-吡喃葡萄糖苷(14),(-)-2-羟基-5-(2-羟乙基)苯-O-β-D-吡喃葡萄糖苷(15),(-)-isolariciresinol(16),isofraxoside(17),2,4,6-trihydroxacetophenone-3,5-di-C-β-D-glucoside(18)。结论:化合物1,13-18为首次从杜鹃花属植物中分离得到,其余化合物均为首次从该种植物中分离得到。
An unusual natural product named 2,4,6-trihydroxacetophenone-3,5-di-C-β-D-glucoside(18) were isolated from aerial parts of Rhododendron lepidotum grows in Tibet,along with other 17 known compounds:hopenol-B(1),lupeol(2),ursolic acid(3),avicularin (4),quercetin (5),myricetin(6),hyperoside (7),myricetin-3 '-O-β-D-xyloside (8),(+)-taxifolin-3-O-α-L-arabinopyranoside (9),( + )-taxifolin-3- O-β-D-glucopyranoside(10),lyoniside(11),confluentin(12),2-(4-hydroxyphenyl)- ethyltriacontanoate(13),2,6-dimethoxy-4-hydroxyphenyl-1-O-β-D-glucopyranoside ( 14),(-)-2-hydroxy-5-(2-hydroxyethyl)phenyl-O-β-D-glucopyranoside(15),(-)-isola-riciresinol(16) and isofraxoside(17).All the compounds were firstly isolated from this plant as well as compounds 1,13-18 were reported occurrence in R.spp.for the first time.The structures were identified based on analyses of spectroscopic data and physico-chemical evidences.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2012年第4期483-489,共7页
China Journal of Chinese Materia Medica
基金
National Natural Science Foundation of China(201142004)
New Century Talents Scheme of the Ministry of Education(NECT-08-0820)
Fundamental Research Funds for Central Universities(SWJTU 2010ZT09)
SWJTU Science Pesearch Funds(2008A17)
关键词
鳞腺杜鹃
苯乙酮双碳糖苷
黄酮
木质素
酚
三萜
Rhododendron lepidotum
acetophenone-di-C-glucoside
flavones
lignin
phenol
triterpene
