摘要
目的 :探讨手术病人急性等容血液稀释自体输血对机体血流动力学、血液生化的影响。方法 :对 3 0例择期手术病人麻醉后放血 (8 0± 2 7)ml·kg-1,用等容量血定安 (gelofusine)进行血液稀释 ,观察急性等容血液稀释前后血流动力学、血液生化指标的变化。结果 :血液稀释后血红蛋白 (Hb)、血球压积 (Hct)和血小板计数 (Plc)下降幅度分别为 13 8% (P <0 .0 5 ) ,17 1% (P <0 .0 5 )和 7 1% (P >0 .0 5 ) ,但仍在临床正常范围内。血液稀释前后平均动脉压(MAP)、心率 (HR)、血氧饱和度 (SpO2 )、心电图 (ECG)均稳定 ,血Na+,K+,Cl-无明显变化。结论 :急性等容血液稀释是一种安全有效的自身输血方法 ,能有效减少或避免异体输血及由此所引起的输血相关疾病的发生 ,应积极推广应用。
To investigate the effects of acute normovolemic hemodilution(ANHD) on hemodynamics and hemobiochemistry during surgery. In 30 patients(ASA Grade Ⅰ～Ⅲ) undergoing selective surgery, ANHD was accomplished by exchanging whole blood(8.0±2.7)ml·kg -1 with an equal volume of gelofusine after induction of anesthesia. The results showed: after ANHD, Hb, Hct and Plc levels respectively decreased by 13.8%(P<0.05), 17.1%(P<0.05) and 7.1%(P>0.05), and yet kept in normal range; MAP,HR,SpO 2, ECG maintained the normal level; and no significant changes were observed in the concentration of Na +, K + and Cl -. ANHD is a safe and effective technique of autotransfusion, and can decrease or avoid the risk of disease transmission. [
出处
《湖南医科大学学报》
CSCD
2000年第1期83-84,共2页
Bulletin of Hunan Medical University
关键词
血液动力学
自血回输
等容血液稀释
blood transfusion,autologous
hemo dynamics
biochemistry
