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胃肠道间质瘤诊治进展 被引量：5

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摘要 胃肠道问质瘤（gastrointe stinals tromalturnour．GIST）是胃肠道最常见的间叶源性肿瘤，被认为起源于肠道蠕动的起搏细胞——Cajal细胞。GIST可发生于食管至肛门的任何部位，极少数可原发于肝脏、附睾、阴道等部位。KIT和PDGFRA的功能性突变是GIST形成的关键因素，其突变可使相应受体及下游的信号通路形成非配体依赖性激活，从而导致细胞周期失控、
作者 于吉人
机构地区 浙江大学医学院附属第一医院胃肠外科
出处 《浙江医学》 CAS 2012年第1期3-5,18,共4页 Zhejiang Medical Journal
关键词 胃肠道间质瘤 CAJAL细胞 诊治 间叶源性肿瘤 PDGFRA 细胞周期失控 GIST 起搏细胞
分类号 R735 [医药卫生—肿瘤]
  • 相关文献

参考文献31

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同被引文献53

  • 1付焱,李恒,金曙,黄东,刘全,孙敏,但超,汪胜胜.双镜联合行胃间质瘤切除术的临床分析[J].中华临床医师杂志（电子版）,2012,6(20):192-193. 被引量：5
  • 2裘华森,吕宾,张勤,周济春,余建法,李青,郑超,茅巍.腹腔镜联合内镜治疗胃肠道占位性病变的临床应用[J].浙江医学,2009(11). 被引量：2
  • 3Kamkousis GC, Singer S, Zheng J, et al. Lapamscopic versus open gas- tric resections for primary gastrointestinal stroma| tumors ( GISTs ) : a size-matched comparison [ J ]. Ann Surg 0ncol, 2011,18 ( 6 ) : 1599- 1605.
  • 4Eisenberg BL, Pipas JM.Gastrointestinal stromal tumors--background, pathology, treatment[J]. Hematol Oncol Clin North Am,20i2,26(6):1239- 1259.
  • 5Kamkousis GC, Singer S, Zheng J, et al. Laparoscopic versus open gastric resections for primary gastrointestinal stromal tumors (GISTs): a size-matched comparison[J]. Ann Surg Oncol,2011,18(6):1599-1605.
  • 6Chen YH, Liu KH, Yeh CN, et aL Laparoscopic resection of gastrointestinal stromal tumor safe, efficient,and comparable oncologic[J]J Laparoe ndosc Adv Surg Tech A,2012,22(8):758-763.
  • 7Kim KH, Kim MC, Jung GJ, et al. Long term survival results for gastric GIST: is laparoscopic surgery for larpe gastric GIST feasible?[J]. World J Surg Oncol,2012,10( 1 ):230.
  • 8Tsujimoto H, Yaguchi Y, Kumano I, et al. Successful gastric submucosal tumor resection using laparoscopic and endoscopic cooperative surgery[J]. World J Surg,2012,36(2):327-330.
  • 9Novitsky YW, Kercher KW, Sing RF, et al. Long-term outcomes of laparoscopic resection of gastric gastrointestinal stremal tumors[J]. Ann Surg,2006,243(6): 738-745.
  • 10De Vogelaere K, Van Loo I, Peters O, et al. Laparoscopic resection of gastric gastrointestinal stromal tumors (GIST) is safe and effective, irrespective of tumor size[J]. Surg Endosc,2012,26(8):2339-2345.

引证文献5

二级引证文献18

浙江医学
2012年 第1期

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