摘要
肿瘤抑素是一种能够有效抑制肿瘤新生血管和肿瘤细胞增殖的生物活性物质,通过双重途径抑制肿瘤生长,具有较强的肿瘤生长抑制作用。肿瘤抑素的生物活性和作用机制逐渐得到揭示,文章对其抗新生血管的活性和作用机制进行综述,并展望其在眼科的应用前景。
Tumstatin is a bioactivator which can effectively suppress tumor growth by inhibiting both angiogenesis of tumor vessels and proliferation of tumor cells.Tumstatin has great ability to cause tumor stasis.The bioactivity and mechanisms of tumstatin have been gradually revealed.The antiangiogenic activity and mechanisms of tumstatin are reviewed in this paper,and the prospect of application of tumstatin in ophthalmology is explored.
出处
《上海交通大学学报（医学版）》
CAS
CSCD
北大核心
2012年第2期214-218,共5页
Journal of Shanghai Jiao tong University:Medical Science
基金
上海市科委白玉兰科研基金(11BA1409700)
上海交通大学医学院自然科学研究基金(11XJ21056)
上海市眼底病重点实验室开放课题基金(07Z22911)~~
