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绝经过渡期和绝经后期妇女使用激素替代疗法的风险探讨 被引量:14

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摘要 目的:分析绝经过渡期和绝经后期妇女使用激素替代疗法的风险和获益。方法:选取2007年1月~2010年1月在玉林市卫生学校附属医院门诊就诊的300例绝经前后的妇女,给予激素替代疗法后,分析其更年期症状改善情况。结果:45岁之前,尤其在40岁以前出现自然或医源性绝经的妇女患心血管疾病及骨质疏松的风险更高。她们可以从激素替代疗法中获益,治疗应至少持续至正常的绝经年龄。结论:激素替代疗法的安全性很大程度上取决于年龄。<60岁的妇女采用激素替代疗法不涉及安全性问题。对于大多数妇女来说,如果在绝经的前几年便开始使用激素替代疗法,那么,在有明确指征的情况下,潜在的益处有很多,而风险很少。
作者 陈晓
出处 《中国妇幼保健》 CAS 北大核心 2012年第6期956-957,共2页 Maternal and Child Health Care of China
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