摘要
目的探讨炎性乳癌患者新辅助化疗前、后血浆中D-二聚体指标变化的临床意义。方法采用胶乳增强免疫比浊法检测18例炎性乳腺癌患者化疗前、后血浆D-二聚体含量。结果炎性乳癌患者新辅助化疗前血浆中D-二聚体比正常对照组高(P<0.01),化疗后D-二聚体含量显著低于化疗前(P<0.01)。结论血浆D-二聚体水平的高低可作为炎性乳癌疗效观察、判断预后的一个指标。
Objective To study patients with inflammatory breast cancer for their plasma D - dimer levels before and after neoadjuvant chemotherapy. Methods Plasma D - dimer levels were measured in 18 patients with, inflammatory breast cancer before and after neoadjuvant chemotherapy using latex - enhanced nephelometry. Results D - dimer plasma levels in patients with inflammatory breast cancer were higher than those in control group before chemotherapy( P 〈 0.01 ). They were significantly elevated after chemotherapy ( P 〈 0.01 ). Conclusions D - dimmer plasma levels could be useful for predicting clinical outcome in patients with inflammatory breast cancer.
出处
《社区医学杂志》
2012年第2期14-15,共2页
Journal Of Community Medicine
关键词
炎性乳癌
D-二聚体
新辅助化疗
Inflammatory breast cancer
D -dimmer
Neoadjuvant chemotherapy