摘要
在硫酸介质中,阿莫西林可以催化溴酸钾氧化甲基橙使其褪色,且褪色程度(△A)与阿莫西林浓度在一定范围内符合朗伯-比尔定律,据此建立了催化光度法测定阿莫西林的新方法。在最优试验条件下,阿莫西林含量在0.70～9.0μg/mL范围内与吸光度呈良好的线性关系,检出限0.33μg/mL,回收率在96%～104%之间。可用于胶囊中阿莫西林含量的测定,结果满意。
Based on the catalytic effects of amoxiciUin on potassium bromate under sulphuric acid medium and the fading the oxidation reactions of helianthine by obeyed the Lambert-Beer law with the concentration of amoxicillin in a certain range, a new catalytic spectrophotometric method was developed Under the optimal conditions, the detection limit for amoxicillin was 0.33 μg/mL and the recovery rate was 96% - 104%. And the linear range for amoxicillin was 0.70 -9.00 μg/mL. The method has been applied to determine amoxiciUin in capsule with satisfying results.
出处
《陕西理工学院学报（自然科学版）》
2012年第1期68-72,共5页
Journal of Shananxi University of Technology:Natural Science Edition
基金
陕西理工学院引进人才科研启动基金资助项目(SLGQD0510)
关键词
阿莫西林
溴酸钾
甲基橙
催化光度法
amoxicillin
potassium bromate
helianthine
catalytic spectrophotometry
