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62例派罗欣注射液不良反应分析 被引量:3

Analysis of adverse reactions in 62 cases of patients with pegylated interferon
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摘要 目的观察我院传染科使用派罗欣注射液不良反应发生的情况,为临床医师用药提供参考。方法从传染科2008年1月至2010年12月使用派罗欣注射液的住院病例中选取62例,所选病例用药前体温(T)和血常规均正常,统计其用药后主要不良反应,对有关数据进行评价分析。结果使用派罗欣注射液的62例住院病人中,有32例用药后出现流感样症状,24例出现血液系统损害(白细胞、血小板减少),其他不良反应6例。结论临床医师在使用派罗欣注射液时应注意其常见的发热、畏寒、肌痛、头痛等类似流感样症状及血液系统损害(白细胞、血小板减少)。 Objective To observe adverse reactions in sixty-two cases of inpatients with pegylated IFNα-2a injections in infectious dept,in order to provide reference for clinician in the course of choosing pegylated IFNα-2a injections.Methods Sixty-two cases of inpatients were chosen who had used pegylated IFNα-2a injections from January 2008 to December 2010,Temperature(T) before medication and blood tests of the selected cases were normal,their adverse reactions after medication were observed,the data were evaluated and analyzed.Results The results showed that in sixty-two inpatients who had used pegylated IFNα-2a injection,thirty-two patients were elevated after treatment in body temperature;twenty-four patients appeared thrombocytopenia after treatment;six patients appeared other adverse reactions.Conclusion In the use of pegylated IFNα-2a,the hospital should pay attention to the common fever,chills,myalgia,headache and similar upper respiratory infection symptoms and blood system damage(WBC and PLT reduce).
出处 《青岛医药卫生》 2012年第1期16-17,共2页 Qingdao Medical Journal
关键词 长效干扰素 派罗欣 不良反应 Long-acting interferon Pegylated IFNα-2a Adverse reaction
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