摘要
目的探讨老年(发病年龄≥60岁)溃疡性结肠炎(UC)的临床、内镜特点及癌变率。方法入组92例UC患者,其中老年组(发病年龄≥60岁)41例,非老年组(发病年龄20～59岁)51例,对2组患者临床、内镜特点及癌变率进行比较分析。结果 2组患者的腹痛、腹泻、脓血便、发热、消瘦、低蛋白血症、贫血、肠外表现、并发症、癌变的发生率比较差异均无统计学意义(P均>0.05)。内镜下,老年组与非老年组病变范围均以直肠+乙状结肠及左半结肠所占比例为主,比较差异无统计学意义(P>0.05)。老年组中病情轻度占75.6%,中重度占24.4%;而非老年组分别为54.9%和45.1%,比较差异均有统计学意义(P均<0.05)。结论老年UC患者的临床表现及病变范围与非老年UC患者相似,但老年UC患者病情相对较轻。
Objective To investigate the clinical and endoscopic features and the canceration rate of the elderly patients with ulcerative colitis（UC）. Methods The 92 patients with UC were collected,the clinical and endoscopic features and the canceration rate were observed and compared between the elderly（age of onset≥60 years） and the young（age of onset 20-59 years） patients. Results There were no significant differences in the incidences of abdominal pain,diarrhea,bloody purulent stools,fever,emaciation,hypoproteinemia,anemia,extraintestinal manifestations,complications and canceration between the two groups（P0.05）.The colonoscope examination showed： the lesions more located at the rectum plus sigmoid colon and left colon both in the elderly patient group and the young patient group,there were no significant differences between the two groups（P0.05）.The mild disease rate of the elderly patient group was 75.6%,the middle or severe disease rate was 24.4%;those of the young patient group were 54.9% and 45.1%,respectively,there were significant differences between the two groups（P0.05）. Conclusion The clinical features and lesions range of the elderly patients are similar to the young patients,and the pathogenetic condition of the elderly patients with UC is lighter than that of the young patients.
出处
《肿瘤基础与临床》
2012年第1期35-37,共3页
journal of basic and clinical oncology
关键词
老年人
溃疡性结肠炎
结肠镜
elderly people
ulcerative colitis
colonoscope
