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选择性门静脉系统置管溶栓治疗肠系膜上静脉血栓疗效观察 被引量:5

Efficacy of thrombolytic therapy on superior mesenteric vein thrombosis by percutaneous transhepatic portal vein catheterization
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摘要 目的探讨经皮经肝穿刺门静脉-肠系膜上静脉置管溶栓治疗肠系膜上静脉血栓(MVT)的临床效果。方法回顾性分析2000年1月至2011年4月通过经皮肝穿门静脉置管溶栓对15例MVT患者的治疗情况及疗效。结果15例患者均成功经皮肝穿门静脉置管,置管后无气胸、胆漏及腹腔内出血。11例患者溶栓效果佳,肠系膜上静脉、门静脉及脾静脉大部分或完全再通,再通率73.3%(11/15),病死率为13.3%。尿激酶总量未超过500万U,未出现全身各系统出血病例。随访6~36个月,无门静脉系统血栓加重和复发病例。结论经皮经肝穿刺门静脉系统置管溶栓技术容易掌握,局部灌注溶栓治疗效果佳,并发症发生率低,可作为MVT治疗的一种选择方法。 Objective To evaluate the therapeutic efficacy of percutaneous transhepatic portal vein catheterization and thrombolysis on superior mesenteric vein thrombosis. Methods The treatment and therapeutic efficacy of 15 cases of patients with superior mesenteric vein thrombosis underwent percutaneous transhepatic portal vein catheterization and thrombolysis from January 2000 to April 2011 were retrospectively analyzed. Results Percutaneous transhepatic portal vein catheterization was performed successfully in 15 patients, without pneumothorax, bile leakage and intra-abdominal hemorrhage after catheterization. Eleven patients had good thrombolytic effect , with majority or complete recanalization on superior mesenteric vein, portal vein and splenic vein. The rate of recanalization was 73.3% , total mortality was 13.3%. The total amount of urokinase was not more than 500 million U, and there was no cases with systemic bleeding. From 6 months to 36 months follow-up, there was no increased portal vein system thrombosis and recurrent cases. ConclusionThrombolysis technique of percutaneous transhepatic portal vein catheterization'is easy to master, and with good effect of local infusion thrombolytic therapy and lower complication rate. It's a selectable treatment for superior mesenteric vein thrombosis.
出处 《中国综合临床》 2012年第3期238-240,共3页 Clinical Medicine of China
基金 河北省医学科学研究重点课题(20100130)
关键词 肠系膜上静脉血栓形成 经皮经肝穿刺门静脉置管溶栓 介入治疗 Superior mesenteric vein thrombosis Percutaneous portal vein cathSterization Thrombolytic Intervention therapy
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