摘要
目的了解鲍氏不动杆菌(ABA)感染的临床分布及其耐药变迁,为临床治疗及预防鲍氏不动杆菌感染提供依据。方法回顾分析医院2008-2010年鲍氏不动杆菌的病区分布与耐药率变化趋势。结果 2008-2010年鲍氏不动杆菌分离率有逐年增多趋势,该菌科室分布以ICU为主,大多来自痰及咽拭子标本;2008-2010年耐药率总体呈上升趋势,耐药率上升最明显的是头孢曲松,从57.55%上升至96.07%,至2010年鲍氏不动杆菌除阿米卡星,头孢哌酮/舒巴坦和米诺环素3种抗菌药物外,耐药率均>50.0%。结论鲍氏不动杆菌耐药现象呈明显上升趋势,多药耐药鲍氏不动杆菌逐年增多,应重视多药耐药菌的预防隔离工作,防止交叉感染的发生,参照药敏结果合理选择使用抗菌药物。
OBJECTIVE To understand the clinical distribution and changes of antimicrobial resistance of Acinetobacter baumannii（ABA）,and provide evidence for the clinical therapy and prevention of ABA infection.METHODS The distribution of ABA in wards and the change tendency of antibiotics resistance were retrospectively analyzed.RESULTS The isolation rate of ABA was increasing year by year from 2008 to 2010.ABA were mainly distributed in ICU,which were mostly isolated from sputum and gullet swabs.The drug resistance rate from 2008 to 2010 showed an increasing tendency,in particular,the resistant rate to ceftriaxone was increased from 57.55% to 96.07%.The antimicrobial resistance rate in 2010 was higher than 50.0% except for the resistance rates to amikacin,cefoperazone/sulbactam and minocycline.CONCLUSION The drug resistance of ABA keeps a significant upward tendency.Multidrug-resistant strains are increasing year by year.More attention should be paid to the prevention and isolation of multidrug-resistant strains to prevent cross infections.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2012年第4期823-825,共3页
Chinese Journal of Nosocomiology
关键词
鲍氏不动杆菌
医院感染
耐药性
Acinetobacter baumannii
Nosocomial infection
Antibiotics resistance
