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Toll样受体及其在雌性家畜生殖中的作用 被引量:1

Toll-like receptors and their role in female livestock reproduction
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摘要 概述了Toll样受体(TLRs)家族的分子结构、识别的配体以及在免疫应答中起的作用。重点介绍了不同家畜中存在的TLRs及其在雌性家畜排卵、受精、妊娠和分娩各生殖过程中的作用,旨在为研制治疗雌性家畜TLR相关疾病的药物提供参考。 This article reviews the Toll-like receptors(TLRs) family,including molecular structures,ligand recognition and their role in immune response.TLRs in different livestock and their role during ovulation,fertilization,pregnancy and parturition in female domestic livestock are emphasized in order to provide references for the development of new medicine to cure TLR mediated diseases in female domestic livestock.
出处 《中国兽医科学》 CAS CSCD 北大核心 2012年第2期216-220,共5页 Chinese Veterinary Science
基金 国家自然科学基金项目(31172335)
关键词 TOLL样受体 雌性家畜 生殖过程 TLRs female domestic reproductive process
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  • 1MIGGIN S M,O'NEILL L A.New insights into the regulation of TLR signaling[J].J Leukoc Biol,2006,80(2):220-226.
  • 2JUNGI T W,FARHAT K,BUGENER I A,et al.Toll-like re-ceptors in domestic animals[J].Cell Tissue Res,2011,343(1):107-120.
  • 3ABRAHAMS V M,MOR G.Toll-like receptors and their role in the trophoblast[J].Placenta,2005,26(7):540-547.
  • 4GIRLING J E,HEDGER M P.Toll-like receptors in the go-nads and reproductive tract:emerging roles in reproductive physiology and pathology[J].Immunol Cell Biol,2007,85(6):481-489.
  • 5KOGA K,MOR G.Toll-like receptors at the maternal-fetal in-terface in normal pregnancy and pregnancy disorders[J].Am J Reprod Immunol,2010,63(6):587-600.
  • 6MATSUSHIMA N,TANAKA T,ENKHBAYAR P,et al.Comparative sequence analysis of leucine-rich repeats(LRRs)within vertebrate toll-like receptors[J].BMC Genomics,2007,8:124.
  • 7FUKATA M,VAMADEVAN A S,ABREU M T.Toll-like re-ceptors(TLRs)and Nod-like receptors(NLRs)in inflammato-ry disorders[J].Semin Immunol,2009,21(4):242-253.
  • 8TAKEDA K,AKIRA S.Toll-like receptors in innate immunity[J].Int Immunology,2005,17(1):1-14.
  • 9张煜,钟波,杨艳,舒红兵.TLRs与RLRs介导的细胞抗病毒反应信号转导及其调节机制[J].细胞生物学杂志,2009,31(4):453-468. 被引量:30
  • 10YU M,WANG H,DING A,et al.HMGB1signals through toll-like receptor(TLR)4and TLR2[J].Shock,2006,26(2):174-179.

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