摘要
样本含量与检验效能估计是研究设计的重要内容之一。本文介绍了拟作单组设计、配对设计和交叉设计定量与定性资料差异性检验时的样本含量和检验效能估计方法,具体地说,就是针对前述的3种设计且为差异性检验的情形,介绍了效应指标为定量和定性资料时估计样本含量和检验效能的计算公式,以及基于公式和借用SAS软件中的POWER过程分别实现样本含量和检验效能估计的方法,并通过实例进行了演示和讲解,对实际工作者在试验设计时正确落实重复原则具有很好的指导作用。
Estimation of sample size and testing power is an important component of research design. This article introduced methods for sample size and testing power estimation of difference test for quantitative and qualitative data with the singlegroup design, the paired design or the crossover design. To be specific, this article introduced formulas for sample size and testing power estimation of difference test for quantitative and qualitative data with the above three designs, the realization based on the formulas and the POWER procedure of SAS software and elaborated it with examples, which will benefit researchers for implementing the repetition principle.
出处
《中西医结合学报》
CAS
2012年第2期154-159,共6页
Journal of Chinese Integrative Medicine
基金
国家科技重大专项"重大新药创制"资助项目(No.2009ZX09502-028)
关键词
统计学
医学
研究设计
样本大小
检验效能
参数估计
statistics, medical
research design
sample size
testing power
parametric estimation
