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正常血糖-高胰岛素血症的研究进展 被引量：5

Research Progress of Normal Glucose Tolerance-Hyperinsulinemia
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摘要 高胰岛素血症是胰岛素抵抗人群为了维持血糖调节平衡的一种代偿表现,与正常血糖-非高胰岛素血症人群相比,其胰岛β细胞功能已经降低,心脑血管疾病的发病率增加,更容易发展成为2型糖尿病或葡萄糖调节受损的状态。控制体质量,适当的运动,服用双胍类及噻唑烷二酮类药物均可通过改善胰岛素敏感性来减轻胰岛β细胞的负荷,从而降低胰岛素水平。 Hyperinsulinemia is a compensatory result of insulin-resistant individuals to maintain glucose homeostasis.Compared with normal glucose tolerance-non-hyperinsulinemia persons,they have a decreased β-cell function and increased incidence of cardiovascular and cerebrovascular disease,and is easier to develop into type 2 diabetes mellitus or impaired glucose regulation.Weight control,appropriate exercise and drugs such as biguanides and thiazolidinediones can improve the sensibility of insulin to ease the load of β-cell,thus decrease serum insulin level.
作者 钟志标 池莲祥 聂本遂 聂雷
机构地区 深圳市宝安区人民医院内分泌科 深圳南山医院内分泌科
出处 《医学综述》 2012年第3期418-420,共3页 Medical Recapitulate
关键词 高胰岛素血症 糖尿病 心脑血管疾病 Hyperinsulinemia Diabetes mellitus Cardiovascular and cerebrovascular disease
分类号 R587 [医药卫生—内分泌]
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参考文献27

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二级参考文献27

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共引文献78

同被引文献44

  • 1许樟荣.癌症与糖尿病[J].中华糖尿病杂志,2009,1(3). 被引量：2
  • 2施亚雄.糖尿病与心血管风险[J].中华糖尿病杂志,2009,1(3). 被引量：4
  • 3张家庆.新的HOMA-IR——从空腹血糖、空腹胰岛素测胰岛素抵抗[J].中华糖尿病杂志（1006-6187）,2005,13(4):245-246. 被引量：54
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引证文献5

二级引证文献11

医学综述
2012年 第3期

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