摘要
当机体受到各种有害刺激时,体内氧化和抗氧化作用失衡,导致产生大量活性氧簇,活性氧簇可通过氧化作用引起细胞死亡和组织损害。近年来,氧化应激对心血管疾病的作用及其机制日益受到人们的广泛关注,大量研究表明氧化应激在动脉粥样硬化、高血压、心烦颤动、心肌缺血/再灌注损伤、心肌病等心血管疾病的发生、发展过程中起重要作用。
When the body encounters harmful stimuli,the unbalance of oxidation and antioxidation in vivo cause a mass of reactive oxygen species which can induce cell death and tissue damage by means of oxidation.In recent years,the relationship of reactive oxygen species and cardiovascular diseases have attracted more and more attention.A growing body of studies showed that oxidation stress played an important part in the development of cardiovascular diseases,such as atherosclerosis,hypertension,atrial fibrillation,myocardial ischemia-reperfusion injury,and cardiomyopathy etc..
出处
《医学综述》
2012年第2期192-194,共3页
Medical Recapitulate
关键词
氧化应激
活性氧簇
心血管疾病
Oxidation stress
Reactive oxygen species
Cardiovascular diseases
