摘要
脑胶质瘤的侵袭常沿着有髓神经纤维和血管基底膜途径进行。MR功能成像包括MRS、PWI和DWI,具有一定的分子成像的能力。MRS代谢物浓度变化可以明确瘤体和瘤周的代谢物变化。Cho/Cr值自近瘤周区向远瘤周区有逐渐降低的趋势,而NAA/Cr则有升高趋势,符合胶质瘤沿白质纤维自近向远侵袭性生长的特点。MRI灌注成像rCBV对胶质瘤分级的预测具有一定价值。MRI弥散成像通过反映组织内水分子的扩散特性反映脑内肿瘤的病理变化,常以扩散张量成(DTI)、表观扩散系数(ADC)和白质纤维束追踪技术(FT)来间接反映胶质瘤的生物学侵袭性特点。MR功能成像在评价脑胶质瘤侵袭性上具有一定价值,临床医生应把传统MRI与多种功能成像技术联合应用来提高MRI对胶质瘤侵袭性的认识。
Glioma is the most frequent primary brain tumor in adult. Invasion is an important biological feature of glioma and is also one of the reasons that gliomas are hard to be cured. Functional magnetic resonance imaging （MRI） is a novel tool to evaluate invasion of glioma. In this article, we reviewed the invasive pattern of gliomas and the insufficiency of routine MRI in the evaluation of glioma invasion. In addition, we also described the employment of functional MRI in the analysis of invasion of gliomas
出处
《中国神经肿瘤杂志》
2011年第4期242-246,共5页
Chinese Journal of Neuro-Oncology
关键词
脑肿瘤
磁共振功能成像
Brain Neoplasm
Functional magnetic resonance imaging
