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周剂量顺铂同步三维适形放射治疗局部晚期非小细胞肺癌临床研究 被引量：3

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摘要 目的探讨周剂量顺铂同步三维适形放射治疗(3D-CRT)局部晚期非小细胞肺癌(NSCLC)的临床疗效和相关影响因素。方法对58例局部晚期NSCLC患者采用3D-CRT联合顺铂同步化疗,总DT64～72Gy,中位剂量68Gy。同步应用顺铂25mg·m-2·周-1,连用6周。结果完全缓解11例,部分缓解35例,稳定12例,进展0例;总有效率(CR+PR)79.31%。中位生存期16.2个月,中位局部无进展生存时间8.7个月。1、2、3年生存率分别为62.09%、31.03%和20.69%。结论周剂量顺铂同步3D-CRT治疗局部晚期NSCLC具有较好的近期与远期疗效,不良反应可耐受。KPS评分、肿瘤大小及放疗剂量为影响近期疗效的独立因素。
作者 顾涛 付占昭 曹晓艳 孙晓东 邸娅 霍新龙 姚薇
机构地区 河北省秦皇岛市第一医院肿瘤科 河北省唐山市工人医院肿瘤科
出处 《河北医药》 CAS 2012年第2期213-214,共2页 Hebei Medical Journal
关键词 非小细胞肺癌 三维适形放疗 同步放化疗 顺铂
分类号 R734.2 [医药卫生—肿瘤]
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参考文献8

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共引文献13

同被引文献26

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河北医药
2012年 第2期

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