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化斑解毒饮治疗系统性红斑狼疮热毒炽盛证的临床研究 被引量:13

CLINICAL STUDY ON SYSTEMIC LUPUS ERYTHEMATOSUS BELONGING TO NOXIOUS HEAT SYNDROME TREATED WITH HUABANJIEDUYIN
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摘要 本研究以中西医结合辨病期与辨证相结合,以化斑解毒饮合常规西药为方法治疗系统性红斑狼疮热毒炽盛证 30例,并设对照组 30例以常规西药治疗。结果表明:治疗组总有效率为 89.9%,高于对照组 76.6%(P<0.05;治疗组病情评分改善优于时照组(P<0.05);在两组治疗主要实验室指标的改善方面,治疗组要优于对照组,但差别无显著性意义(P>0.05);治疗组在发热、斑疹、脱发、乏力、消化道、神经系统及心悸症状的改善方面明显优于对照组(P<0.05,P<0.05);治疗组在感染、出血、高血压并发症方面明显少于对照组(P<0.05,P<0.01)。本研究说明化斑解毒饮合常规西药组辨证治疗系统性红斑狼疮能较好地控制病情及减少西药所致的副作用。 30patients with Systemic Lupus Erythematosus(SLE) belonging to noxious heat syndrome treated with Huaduxiaobanyin and routine westernal therapy on the basis of combination of differentiation of syndromes with diseases,meanwhile, 30case only treated with westernal therapy were taken as control. The results showed that the total effective rate of treatment group was 89.9%, that of control was 76.7%,there was significant difference between two groups (P<0.05);the improvement of symptoms data was more significant in treatment group than that in control (P<0.05);the improvement of laborary examination data in treatment group was superior to that in control group,but no significant difference (P> 0.05),the improvement symptoms as fever、macular eruption、baldness、fatigue. intestine, nervous system and palpitation in treatment group was highly superior to that in control group(P< 0.05- 0.01),and the incidence of side-effect in treatment was lower obviously than that of control group (P< 0.05- 0.01 ), All these indicated that combination westernal medicine with huabanjieduayin could effectively treat SLE, control the development of SLE and decrease the side-effects
作者 郑少平
出处 《中国中医药科技》 CAS 2000年第1期3-5,共3页 Chinese Journal of Traditional Medical Science and Technology
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  • 1..中药新药临床研究指导原则,第一辑[S].卫生部,1993..

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