摘要
目的探究不同术后镇痛方法对骨科老年患者皮质醇和知功能的影响。方法本文共收集90例2011年3月～2011年12月在骨科就诊的老年患者作为观察对象,随机分为两组,分别采用PCEA和PCIA进行术后镇痛,比较两组患者的镇痛效果、皮质醇浓度及后早期认知功能的情况。结果 PCEA组术后24h及术后48h的VAS评分明显低于PCIA组(P<0.05);两组患者的皮质醇浓度于术后24h及术后48h明显升高,PCIA组明显高于PCEA组,差异有统计学意义(P<0.05);术后24h及术后48h两组患者的MMSE评分逐渐降低,PCEA组患者的MMSE评分明显高于PCIA组,差异有统计学意义(P<0.05)。结论舒芬太尼联合其它药物多模式镇痛应用于PCEA,对骨科老年患者起着安全强效的镇痛作用,减少应激反应,降低皮质醇浓度,利于术后早期认知功能的恢复,可作为常规术后镇痛方法在临床上推广使用。
Objective To investigate the the influence of early POCD and cortisol between Different Postoperative analgesia of orthopaedic elderly patients. Methods Select 90 orthopaedic elderly patients during March 2011 to December 2011 in our hosspital. And put them into two groups as PCIA group and PCEA group. Compare the analgesic effect l cortisol concentration and early after cognitive function between two groups of patients. Results PCEA 24 h after group and in 48 h of the VAS score was significantly lower than the PCIA group （P〈0.05）. Two sets of patients in 24 h after cortisol concentration and postoperative 48 h increased significantly, PCIA group was significantly higher than the PCEA groups, the difference was statistically significant （P〈 0.05）. Postoperative 24 h and postoperative 48 h two sets of patients MMSE score gradually reduced, PCEA groups of patients was higher than the MMSE score PCIA groups, the difference was statistically significant （P〈0.05）.Conclusion It shows Sufentanil together with other drugs obvious advantages in PCEA pattern analgesia which is worthy of clinical promotion or can be recognized as a prior choice in clinical anesthesia.
出处
《当代医学》
2012年第4期3-4,共2页
Contemporary Medicine
