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固定制剂拉坦噻吗滴眼液降眼压效果的短期临床观察 被引量：3

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摘要 前列腺素类滴眼液的出现为药物治疗青光眼提供了新的途径，其降眼压机制主要是通过增加葡萄膜巩膜房水引流，而不减少房水生成。噻吗洛尔眼液是一种非选择性的β-肾上腺素能受体阻滞剂，其降眼压作用原理是降低眼房水的形成能力，抑制眼压上升。
作者 陆士恒 谭烨
机构地区 上海市浦东新区公利医院眼科
出处 《中国眼耳鼻喉科杂志》 2012年第1期62-63,共2页 Chinese Journal of Ophthalmology and Otorhinolaryngology
关键词 降眼压机制 滴眼液 临床观察 Β-肾上腺素能受体阻滞剂 制剂 前列腺素类 葡萄膜巩膜 降眼压作用
分类号 R775 [医药卫生—眼科]
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参考文献12

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  • 4Kass MA,Heuer DK,Higginbotham E J,et al.The Ocular Hypertension Treatment Study:a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma[J].Arch Ophthalmol,2002,120 (6):701-713.
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二级参考文献20

  • 1石晶明,蒋幼芹,葛坚,刘磊,孙兴怀,陈晓明,余敏斌,孙丽,郭文毅,李茅.派立明与贝特舒联合用药对青光眼和高眼压症疗效的多中心研究[J].中国实用眼科杂志,2004,22(12):969-972. 被引量：6
  • 2余敏斌,方敏,葛坚,黄圣松.1%派立明滴眼液联合0.25%贝特舒混悬液的临床降眼压疗效及安全性观察[J].眼科学报,2005,21(4):137-140. 被引量：4
  • 3Baudouin C, Garcher C, Haouat N, et al. Expression of inflammatory membrane markers by conjunctival cells in chronically treated patients with glaucoma [ J ]. Ophthalmology, 1994, 101(3) :454 -460.
  • 4Pisella PJ, Debbasch C, Hamard P, et al. Conjunctival proinflammatory and proapoptotic effects of latanoprost and preserved and unpreserved timolol: an ex vivo and in vitro study [ J ]. Invest Ophthalmol Vis Sci, 2004, 45 (5) : 1360 - 1368.
  • 5Berdy GJ, Abelson MB, Smith LM, et al. Preservative - free artificial tear preparations. Assessment of corneal epithelial toxic effects[J]. Arch Ophthalmol, 1992, 110 (4) : 528 -532.
  • 6Noecker RJ, Herrygers LA, Anwaruddin R. Corneal and conjunctival changes caused by commonly used glaucoma medications [ J ]. Cornea, 2004, 23 (5) : 490 - 496.
  • 7Lark KK, Pasha AS, Yan X, et al. The effect of latanoprost and brimonidine on rabbit subconjunctival fibroblasts [J]. J Glaucoma, 1999, 8(1) : 72 -76.
  • 8Debbasch C, Brignole F, Pisella PJ, et al. Quaternary ammoniums and other preservatives' contribution in oxidative stress and apoptosis on Chang conjunctival cells [ J ]. Invest Ophthalmol Vis Sci, 2001,42(3) : 642 -652.
  • 9De Saint Jean M, Debbasch C, Brignole F, et al. Toxicity of preserved and unpreserved antiglaucoma topical drugs in an in vitro model of conjunctival cells [ J ]. Curr Eye Res, 2000, 20 (2) : 85 - 94.
  • 10Doughty MJ. Twice - daily use of a chlorobutanol -preserved artificial tear on rabbit corneal epithelium assessed by scanning electron microscopy [ J]. Ophthalmic Physiol Opt, 1992, 12(4):457-466.

共引文献15

同被引文献24

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二级引证文献24

中国眼耳鼻喉科杂志
2012年 第1期

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