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microRNA-155的免疫调控作用 被引量：6

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摘要 miR-155是一种具有免疫调控功能的微小RNA,它能够在转录后降解靶信使RNA或者抑制靶基因的翻译。最近的研究发现它对树突状细胞、巨噬细胞、B细胞、T细胞及调节性T细胞等免疫细胞的分化发育和功能都具有重要的调控作用,某些病毒的miRNA与miR-155具有同源性,在免疫调控中也可能发挥相同作用。随着miRNA研究的深入,miR-155的更多调控作用将浮出水面,尤其是将为探究免疫相关疾病的病理机制和治疗措施提供新思路。
作者 张波 田野苹
机构地区 第二军医大学免疫学教研室
出处 《现代免疫学》 CAS CSCD 北大核心 2012年第1期80-83,共4页 Current Immunology
关键词 MIR-155 免疫细胞 免疫调控
分类号 R392 [医药卫生—免疫学]
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参考文献30

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同被引文献76

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引证文献6

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现代免疫学
2012年 第1期

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