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尿香草扁桃酸测定对锰中毒早期诊断的意义 被引量:1

The value of urinary vanillylmandelic acid(VMA) for early diagnosis of manganese poisoning.
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摘要 本文对440名锰作业工人进行了尿香草扁桃酸(VMA)测定,结果明显高于对照纽,差异非常显著(P<0.001)。本文还讨论了锰接触者尿VMA升高的机理。作者认为尿VMA可作为锰中毒早期诊断较为客观的指标。 Urinary VMA of 440 workers exposed to manganese fumes or dusts were determined. It was shown to be highly increased than that of the control group(P<0.001). The mechanism of urinary VMA increase of the exposed workers was discussed. It was considered that the urinary VMA was useful in early diagnosis of manganese poisoning.
出处 《职业医学》 CAS 1990年第1期5-6,共2页 China Occupational Medicine
关键词 香草扁桃酸 锰宁毒 诊断 VMA, manganese poisoning, diagnosis
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参考文献1

  • 1Girja S. Shukla,Satya V. Chandra. Striatal dopamine turnover and l-dopa treatment after short-term exposure of rats to manganese[J] 1981,Archives of Toxicology(3):191~196

同被引文献9

  • 1姜岳明,陆继培,谢佩意,马富诗,梁宏柱,张凤生.锰对接触男工神经内分泌系统影响的初探[J].铁道劳动安全卫生与环保,1996,23(2):103-105. 被引量:3
  • 2陈骥光.锰对工人全血胆碱酯酶活性的影响[J].中华预防医学杂志,1994,28(4):247-247.
  • 3陈成章 周炯亮.锰中毒发病原理的研究[J].医学参考资料,1975,(3):120-121.
  • 4Lai JCK, Chan AWK, Leung TKC.Neuro-chemical changes in rats chronically treated with a high concentration of manganese chloride[J]. Neurochem Res, 1992, 17(9): 841 ~847.
  • 5Chandra SV, Shukla GS. Manganese encephalopathy in growing rats[ J]. Environ Res, 1978,15: 28 ~ 37.
  • 6Lai JCK, Leung TKC, Lim L. The ontogeng of acetylcholinesterase activities in rat brain regions and the effect of chronic treatment with manganese chloride [ J ]. J Neurochem, 1982,39:1767 ~ 1769.
  • 7Misiewiciz A, Karmolinski M. Acetylcholinesterase activity in erythrocytes of workers engaged in the production of ironmanganese alloys[J]. Med Pr, 1992,43( 1 ) :47 ~ 51.
  • 8Ai LB, Chua LH, New AL, et al. Urinary homovanillic acid (HVA) and vanillymandelic acid (VMA) in workers exposed to manganese dust [ J ]. Biological Trace Element Research, 1998,64: 89 ~ 99.
  • 9王天奎,冯润金.环境锰对儿童神经系统的影响[J].国外医学(医学地理分册),1992,13(2):53-55. 被引量:2

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