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环孢素A的慢性肾毒性 被引量:10

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摘要 环孢素A的慢性肾毒性是影响临床同种肾移植术后病人长期存活的重要因素之一,其机理仍不清楚。目前研究认为,转化生长因子β等细胞因子在环孢素A慢性肾毒性发病中起重要的作用。本文对这方面的研究作一综述。
出处 《国外医学(泌尿系统分册)》 2000年第1期16-19,共4页 Foreign Medical Sciences(Urology and Nephrology Foreign Medical Sciences)
关键词 环孢素A 肾毒性
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参考文献10

  • 1Burdmann EA,Andoh TF Nast CC,et al. American Journal of Physiology . 1995
  • 2Shihab FS,Andoh TF,Tanner AM,et al. Kidney International . 1996
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同被引文献42

  • 1高坤.孙伟教授以益肾清利活血法治疗慢性肾小球疾病的经验[J].江苏中医药,2004,25(11):19-21. 被引量:28
  • 2李昕,徐兵,张莉,张友元,南小新.熊去氧胆酸与胆维他联合治疗环孢素所致肝损害的疗效观察[J].中南药学,2006,4(5):390-391. 被引量:3
  • 3史伟.邹燕勤教授治疗慢性肾功能衰竭经验介绍[J].新中医,2007,39(3):17-18. 被引量:6
  • 4Shankland SJ, Scholey JW, LY H, et al. Expression of transforming growth factor-β1 during diabetic renal hypertrophy. Kidney Int, 1994, 46:430.
  • 5Kaneto H, Morrissey J, McCracken, et al. Enalapril reduces collagen type Ⅳ synthesis and expansion of the interstitium in the obstructed rat kidney. Kidney Int, 1994, 45:1637-1647.
  • 6马腾骧.肾移植免疫学基础中有关临床的三个问题.见:郭应禄主编:肾移植进展.北京:北京医科大学出版社,2002:25
  • 7Lee DB. Cyclosporine and the renin-angiotensin axis[J].Kidney Int, 1997, 52(1): 248-260.
  • 8Lassila M. Interaction of cyclosporine A and the renin-angiotensin system; new perspectives[J]. Curr Drug Metab,2002,3(1) : 61-71.
  • 9Rosen S, Greenfeld Z, Brezis M. Chronic cyclosporine-induced nephropathy in the rat. A medullary ray and inuer stripe injury [J]. Transplantation. 1990, 49 (2): 445-452.
  • 10Shihab FS, Andoh TF, Tanner AM, et al. Role of transforming growth factor-beta 1 in experimental chronic cyclosporine nephropathy[J]. Kidney Int, 1996, 49 (4) : 1 141 - 1 151.

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