摘要
66例血压偏高少儿(HBP组)服牛磺酸前及连续服牛磺酸3周后,分别进行OGTT及盐敏感性试验,测定服牛磺酸前后的胰岛素、血清儿茶酚胺及红细胞游离Ca^(++)水平,并与66例按年龄及性别配对的正常血压少儿(NBP组)比较。结果显示:牛磺酸可使OGTT曲线的峰值水平、血压、胰岛素、血浆儿茶酚胺与红细胞内游离Ca^(++)浓度显著降低,但不伴有空腹血糖的改变。盐敏感性在服用牛磺酸后显著下降,但停服30天后又恢复至以前状态。提示牛磺酸可能对改善少儿初始血压高者的胰岛素抵抗及盐敏感性有显著作用。
OGTT, Salt - sensitivity test, plasma insulin, plasma catecholamine and RBC free Ca concentration was measured on 66 cases of higher level blood pressure in children (HBP group) before and after 3 weeks of successive taurinc given orally,and was compared with 66 cases normal subjects (NBP group,matched with age and sex) .The results showed that: Taurine could decline the peak value of OGTT, also, the blood pressure, plasma insulin level, plasma catecholamine and RBC free Ca concentration had a significantly decrease in HBP group. But there no obviously change in fast glucose. The salt - sensitivity was distinctly reduced by taurine given orally, but recovered original status by stopping taurine supplement. these results suggest that taurine may help in improvementinsulin - resistant and salt - sensitivity phenomenon of higher level blood pressure in children.
出处
《医学研究通讯》
2000年第1期13-16,共4页
Bulletin of Medical Research
基金
国家自然科学基金
卫生部基金
关键词
牛磺酸
青少年
高血压
胰岛素
盐敏感性
Taurine Children Hypertension Insulin Salt - sensitivity
