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脑转移瘤的立体定向放射外科治疗24例报道

STEREOTACTIC RADIOSURGERY FOR BRAIN METASTATIC TUMOR——REPORT OF 24 CASES
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摘要 目的 探讨立体定向放射外科(SRS)治疗脑转移瘤的效果。方法 以全脑放疗加SRS或单用SRS治疗24 例(30 病灶)脑转移瘤。结果 大多数病例在SRS后1~2 周获不同程度的症状改善,肿瘤反应率为89 % ,平均存活期为10 月。结论 SRS是治疗小而边界清楚的脑转移瘤的有效手段,肿瘤控制率可达80 % 以上,SRS加全脑放疗可改善肿瘤控制率。 Objective Efficacy of stereotactic radiosurgery (SRS) on brain metastatic tumors was evaluated. Methods 24 cases (30 lesions) of brain metastatic tumors were treated with whole brain irradiation plus SRS or simple SRS. Results 1~2 weeks after SRS, most cases' symptoms were improved somewhat, the tumor therapeutic response rate was 80 %, and the average survival time after SRS was 10 months. Conclusion SRS is an effective therapy for the small and clear cut brain metastatic tumors. The tumor control rate could be over 80 %, and can be improved by SRS plus whole brain irradiation. SRS can also be used for post irradiation recurrence of brain metastasis.
机构地区 解放军总医院
出处 《肿瘤》 CAS CSCD 北大核心 2000年第1期46-47,共2页 Tumor
关键词 脑肿瘤 放射外科手术 肿瘤转移 立体定向术 Brain neoplasms Radiosurgery Neoplasm mteastasis
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参考文献3

  • 1[1]Wong WW, Schild SE, Sawyer TE, et al. Analysis of outcome in patients reirradiated for brain metastases[J]. Int J Radiat Biol Phys, 1996,34:585
  • 2[2]Moriarty TM, Loeffler LS, Black PM, et al. Long-term follow-up of patients treated with stereotactic radiosurgery for single or multiple brain metastases[M]. In: Kondziolka D (ed): Radiosurgery. Basel, Karger, 1996, vol 1:83
  • 3[3]Alexander EⅢ, Moriarty TM, Davis RB, et al. Stereotactic radiosurgery for the definitive, noninvasive treatment of brain metastases[J]. J Natl Cancer Inst, 1995,87:34

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