摘要
:〔目的〕对比观察阿霉素(ADM)多相脂质体与游离ADM治疗晚期肝癌近期疗效及副作用。〔方法〕1997年3月～1998年6月87例晚期肝癌患者,随机分成两组,A组为ADM多相脂质体介入化疗组(治疗组),B组为游离ADM介入化疗组(对照组)。〔结果〕平均生存期1年生存率两组无明显差别,近期疗效A组优于B组,毒副反应A组较B组轻。〔结论〕两种治疗方法平均生存期无明显差别,ADM多相脂质体介入化疗可提高近期疗效,降低毒副反应,提高病人生活质量。
urpose〕To compare the survival rate and side effect of doxorubicin (ADM) liposome therapy and ADM therapy for liver cancer.〔Methods〕Eighty seven patients with advanced liver cancer were divided into two groups:Group A treated by ADM liposome chemotherapy and group B, by ADM chemotherapy.〔Results〕The mean survival and 1 year survival rate showed no significant difference in both groups.However,patients in Group A showed better short term effect and less side effects than those in Group B.〔Conclusion〕ADM Liposome chemotherapy can increase the short term effect,reduce side effect and improve patient's quality of life.
