摘要
目的 :探讨脐血联合 Mx AE方案治疗难治性急非淋白血病的效果。方法 :脐血联合 Mx AE方案治疗难治性急非淋白血病 2 1例 ,难治性 14例 ,复发性 7例。治疗方案 :米托蒽醌 ( Mx) 10 m g/ d、l d～ 3 d;阿糖胞苷( Ara- C) 15 0 mg/ d,l d～ 7d;足叶乙式 ( VP1 6) 10 0 mg/ d,l d～ 5 d。3种药物均静滴 ,3 d～ 7d为一疗程。化疗第 1周、第 2周输脐血 ,每周 3个～ 5个单位。结果 :完全缓解率 ( CR) 66.7% ,骨髓抑制 18例。化疗第 2周、第 3周 ,WBC>3 .0× 10 9/ L ,Plt>5 0× 10 9/ L分别为 16例、2例。无化疗相关死亡。食欲恢复快 ,骨髓抑制期短。结论 :脐血辅助Mx
Objective:To study the effects of treatmect in combination fetal blood and MxAE for refractory acute nonlymphocytic leukemia.Methods:21 cases of R ANLL was treated with combination fetal blood and MxAE in cluding Mx 10 mg/d(l d～3 d),Ara C 150 mg/d(1 d～7 d),Etoposide(VP 16 )100mg/d(1 d～5 d),all of them was transfused for 3 d～7 d as one course.Results:complete remission rate was 66.7%,18 cases of them bone marrow proliferation was impressed neatly.No patients died of infection or other complication.Conclusion:Protocol of the fetal blood and MxAE was a effective way for treratment of refractory acute nonlymphocytic leukemia in primary hospital.
出处
《白血病》
2000年第1期35-36,共2页
