摘要
目的了解医院门诊输液中抗菌药物的使用情况,探讨用药合理性及干预策略,为临床医师合理使用抗菌药提供参考,为职能部门的管理提供依据。方法抽查2010年1月1日至2010年10月1日之间门诊输液患者使用抗生素处方1480份,以抗菌药物使用情况、药物利用指数(DUI)为指标分析用药合理性等方面,对抗菌药物的应用进行综合性评价。结果门诊使用输液抗生素排前三位为氟喹诺酮类、林可霉素类、β-内酰胺类,单药抗生素使用最多81.82%(1 211例),不合理使用抗生素处方占抗菌药物处方15.51%(228例),抗生素给药间隔时间不当占不合理处方比例为73.68%(168例),克林霉素的药物利用指数(DUI)大于1。结论该院门诊抗菌药物使用基本合理,但仍存在一定问题,需采取相应干预策略来进一步提高我院合理应用抗生素水平。
Objective To study the condition of antibiotics application in the clinic and to explore rationality of antibiotics application and intervention strategies,to provide reference for clinicians to use antibiotic reasonably and managing basis for the functional departments.Methods Selective examinations were made in 1 480 prescriptions in which antibiotics was used in the clinicof our hospital from 2010 January 1 to October 1,the condition of antibiotic application,and drug use index(DUI) were used as index to analyze rationality of antibiotics application and comprehensive evaluation was made on antibiotic application.Results Fluoroquinolones、Lincomycin、β-lactams were the three antibiotics used most frequently in infusion in the clinic,single antibiotic use accounted for 81.82%(1 211 cases) was in the first place,unreasonable use in antimicrobial prescription accounted for 15.51%(228 cases),unreasonable intervals of using antibiotics accounted for 73.68%(168 cases),drug use index DUI) of Clindamycin was more than 1.Conclusion Antibiotics Application was basically reasonable in the clinic in our hospital,but there still existed certain problems,appropriate intervention strategies should be taken to improve the reasonability of antibiotics application.
出处
《吉林医药学院学报》
2011年第2期84-87,共4页
Journal of Jilin Medical University
关键词
抗菌药物
应用分析
干预策略
antibiotic
application analysis
intervention strategies