摘要
目的评价中国2005~2010年报告乙型病毒性肝炎(乙肝)的流行病学特征,探索监测系统病例报告、实验室诊断中存在的问题,为指导急性乙肝病例的监测提供依据。方法对2005~2010年中国疾病预防控制信息系统网络直报的乙肝病例的流行病学特征进行分析。结果 2005~2009年,报告的乙肝病例数整体呈上升趋势,2010年首次出现下降。监测报告病例中以慢性乙肝为主,急性乙肝占8%。全人群报告急性乙肝病例发病率从2005年的7.5/10万下降到2010年的5.6/10万;<15岁病例构成比由5.56%下降到1.92%,<15岁人群急性乙肝发病率从2005年的1.23/10万下降到2010年的0.46/10万。结论中国急性乙肝报告病例已经明显下降,<15岁人群下降更为明显。需加强急性乙肝病例的诊断、报告,提高乙肝实验室诊断能力,规范实验室诊断流程和检测项目。
Objective To analyze the epidemiological characteristics of reported hepatitis B between 2005 and 2010, to determine the influencing factors on hepatitis B case reporting and laboratory testing, and to provide the suggestion for improving surveillance of hepatitis B. Methods We analyzed the data of hepatitis B from China information system for disease control and prevention, which is computer based dataset. Results There was a increasing trend of hepatitis B morbidity during 2005 and 2009, and Slight decreased in 2010 for the first time. Among reported hepatitis B cases, only 8 % was acute. The morbidity of acute hepatitis B was decreased from 7.5/100,000 in 2005 to 5.6/100,000 in 2010, the proportion of hepatitis B under 15 years old among reported decreased from 5.56% to 1.92% in same period; morbidity for population under 15 years old was decreased from 1.23/100,000 in 2005 to 0.46/100,000 in 2010. Conclusion The morbidity of acute hepatitis has been decreasing, especially among population under 15 years old. China should enhance the case diagnosing and reporting, to improve laboratory capacity for standard procedure.
出处
《中国疫苗和免疫》
CAS
2011年第6期483-486,559,共5页
Chinese Journal of Vaccines and Immunization
基金
国家科学技术重大专项艾滋病和病毒性肝炎等重大传染病防治专项"我国乙型病毒性肝炎免疫预防策略研究"课题(编号:2008ZX10002-001)