摘要
目的探讨糖尿病心肌病（DC）患者心率震荡（HRT）的变化及其临床意义。方法对DC患者33例及对照组30例进行24h动态心电图检查，分别计算震荡初始（TO）和震荡斜率（TS），比较两组患者TO及TS均值，并对TO、TS与24h正常窦性心律RR间期的标准差（SDNN）及左室舒张末内径（LEVDD）进行相关性分析。结果DC组的TO值高于对照组[（-0．38±0．12）％与（-1．88±0．13）％；t=7．38，P=0．01]，TS值低于对照组[（2．02±0．82）ms／R-R与（9．72±1．18）ms／R—R；t=18．69，P=0．02]；TO与SDNN及LEVDD有相关性（r=-0．35，P=0．02；r=0．68，P=0．01），TS亦与SDNN及LEVDD有相关性（r=0．45，P=0．01；r=-0．39，P=0．03）。结论DC患者HRT现象明显受损。
Objective To study the changes and clinical significance of heart rate turbulence （HRT） in patients with diabetic cardiomyopathy. Methods 24h Holter EGG recordings were examined in 33 patients with diabetic cardiomyopathy （DC）and 30 patients in the control group. Turbulence onset （TO）and turbulence slope （TS） were calculated from Hoher recordings. The mean value of TO, TS between the two groups were compared, the relativity among TO,TS,SDNN and LEVDD were analyzed as well. Results TO was significantly higher in the DC group compared with the control group[ （ - 0.38 ± 0. 12）% vs （ - 1.88 ± 0. 13）% ,t = 7.38,P =0. 01 ） ]. TS in the DC group was significantly lower than that in the control group [ （ 2. 02 ± 0. 82 ） ms/R-R vs （9. 72 ± 1.18） ms/R-R,t = 18. 69,P =0. 02） ]. TO was significantly related to SDNN（r = -0. 35,P =0. 02） and LEVDD （ r = 0. 68 ,P = 0. 01 ）, TS was also significantly related to SDNN （ r = 0.45, P = 0. 01 ） and LEVDD （ r = - 0. 39, P = 0. 03 ）. Conclusion The manifest of heart rate turbulence is significantly impaired in patients with diabetic cardiomyopathy.
出处
《中国综合临床》
2012年第2期169-171,共3页
Clinical Medicine of China
关键词
窦性心率震荡
糖尿病心肌病
室性早搏
Heart rate turbulence
Diabetic cardiomyopathy
Premature ventricular
