摘要
目的探讨研究静脉滴注丹参注射液发生不良反应的类型及因素,为临床用药提供依据。方法对2007年1月2010年12月82例因静脉滴注丹参注射液发生不良反应的患者资料进行回顾分析,并对其相关因素进行分析。结果男性的不良发生率高于女性,不良反应发生年龄多为中、老年患者,并且不良反应多发生在输液30min内,多为Ⅰ型过敏反应。结论对丹参注射液应严格控制生产工艺流程,临床用药要掌握适应证,以避免不良反应的发生。
Objective To investigate the types and factors of adverse reactions caused by intravenous infusion of Danshen injection,in order to provide basis for clinical drug application.Methods We retrospectively analyzed the clinical records of 82 patients with adverse reaction to intravenous infusion of Danshen injection from January 2007 to December 2010.Results Adverse reaction incidence was higher in males than females,and it mainly occurred in patients of middle or old ages.Most of the adverse reactions happened within 30 minutes of the infusion.Type-I allergic reaction was more commonly observed.Conclusion In order to avoid the occurrence of adverse reactions,Danshen injection production process should be strictly controlled,and indications should be considered carefully in clinical medication.
出处
《华西医学》
CAS
2011年第12期1856-1858,共3页
West China Medical Journal
关键词
丹参注射液
不良反应
回顾性研究
Danshen injection
Adverse reaction
Retrospective study
