摘要
我国艾滋病病毒(HIV)感染人群中结核病的发病率高,造成了严重的疾病负担。提高潜伏结核和活动性结核的诊断准确性,对控制HIV病人中结核病的治疗和控制至关重要。该文总结了近年来出现、发展并完善的一种新的结核诊断技术,即结核杆菌特异性酶联免疫斑点技术,及其在HIV人群中的相关研究结果,并着重对该技术在潜伏结核和活动性结核的诊断、治疗效果监测以及结核相关性免疫重建炎症反应综合征中的应用进行了评价。
High prevalence of tuberculosis in Chinese human immunodeficiency virus（HIV） ＋ population leads to enormous disease burden. Improving the diagnostic accuracy for active and latent tuberculosis is a key issue for both treatment and prevention of HIV associated tuberculosis. To facilitate this effort, this review summarizes the relevant researches in HIV＋ population, regarding tuberculosis specific ELISPOT, a new diagnostic testing developed within the past decade, with emphasis on its application in diagnosis, treatment and response monitoring, and evaluation of immune reconstruction inflammatory syndrome.
出处
《中国艾滋病性病》
CAS
2011年第6期708-710,714,共4页
Chinese Journal of Aids & STD
基金
国家重点基础研究发展计划(973)研究项目(2006CB04201)~~
