摘要
目的:提高处方质量,促进临床合理用药。方法:从2010年约49万张门诊处方中,每月随机抽取100张,按照《医院处方点评管理规范(试行)》要求,点评用药合理性。结果:1 200张处方中,平均每张处方使用3.1种药品,抗菌药物使用率为33.7%(404/1 200),注射剂使用率为32.8%(393/1 200),使用基本药物占处方用药的32.5%(390/1 200),药品通用名使用率为92.8%(1 113/1 200),平均每张处方金额151.4元,合理处方所占比例为65.1%(781/1 200)。不合理处方中,不规范处方189张,占45.1%;适应证不适宜处方76张,占18.1%;用法与用量不适宜处方56张,占13.4%;遴选药品不适宜处方51张,占12.2%;药品剂型或给药途径不适宜处方20张,占4.8%;有配伍禁忌或不良相互作用处方14张,占3.3%;超常处方9张,占2.1%;重复给药处方4张,占1.0%。结论:通过处方点评及多种干预措施,合理处方百分率从2010年1月份的22.0%上升到12月份的98.0%,处方点评取得了显著成效。
OBJECTIVE:To improve prescription quality and promote clinical rational drug use.METHODS: Among the total 490 000 outpatient prescriptions in 2010,100 were selected monthly for a statistical analysis with regard to the rationality of drug use in accordance with "Hospital Practice of Prescription Reviews(Trial)".RESULTS: Of the 1 200 prescriptions sampled,an average of 3.1 drugs were prescribed per prescription;33.7%(404/1 200) involved use of antibiotics,32.8%(393/1 200) injections and 32.5%(390/1 200) essential drugs;92.8%(1 113/1 200) prescribed drugs in generic names;the average drug cost per prescription stood at 151.4 Yuan;65.1%(781/1 200) were rational prescriptions.In the 419 irrational prescriptions,189(45.1%) involved non-standard drug use,76(18.1%) inappropriate in indications,56(13.4%) in dosage and administration,51(12.2%) drug choice,20(4.8%) dosage form or route of administration,14(3.3%) incompatibility or drug interaction,9(2.1%) off-label use,and 4(1.0%) repeated drug use.CONCLUSION: The prescription comment together with multiple intervention measures achieved striking effectiveness,which caused increase of the rate of rational prescriptions from 22.0% in January to 98.0% in December in 2010.
出处
《中国医院用药评价与分析》
2011年第12期1145-1147,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
处方
点评
合理用药
Prescription
Comments
Rational drug use